Effects Of Glycine Max And Sesamum Indicum On Reproductive Parameters In Male Wistar Rat Offsprings

Jesse-Abraham Piriye; Amah-Tariah Fortune

Authors

Jesse-Abraham Piriye Department of Science Laboratory technology, School of Science and Technology, Captain Elechi Amadi Polytechnic, Rumuola, P.M. 5936 Port Harcourt
Amah-Tariah Fortune Department of Human Physiology, Faculty of Basic Medical Sciences, University of Port Harcourt, East West Road, P.M.B, 5323, Choba Port Harcourt.

Keywords:

Soya Bean (Glycine max), Sesame Seed (Sesamum indicum), phyto-oestrogens

Abstract

Glycine max and Sesamum indicum are generally perceived to be safe and so they are normally consumed freely especially during the critical period of gestation and lactation. The disruptive properties of Glycine max and Sesamum indicum were investigated on the offsprings of pregnant Wistar rats. Fifteen (15) Male and thirty (30) female Wistar rats were paired to procreate 30 male pups. The adult rats were divided into 6 groups: Group 1 served as Control, Group 2 was treated with Clomiphene, Group 3 had 50mg Soya Beans, Group 4 had 100mg Soya Beans, group 5 had 50mg Sesame Seeds and group 6 had 100mg Sesame seeds. After a 9week experimental period, the study animals were sacrificed and blood samples taken as well as tissues harvested under standard procedures and analyzed. The results showed that Soya Beans and Sesame Seeds caused changes in male reproductive hormones- Testosterone-High dose Sesame seed group (2.54± 0.21 and 3.58± 0.57 )ng/ml, when compared to the control, at p<0.01; FSH (0.19± 0.03/0.28±0.01)mlu/ml and LH (00.43±0.02/0.94±0.18)mlu/ml for Low dose Sesame seed when compared to the control at p<0.05, Low dose Soya group also experienced a fall in FSH levels (0.19±0.01/0.28±0.01) mlu/ml, when compared to the control at p<0.05. The decrease in the FSH and LH hormonal levels could lead to infertility, low sex drive, delayed onset of puberty while increased level of testosterone can increase and improve sperm quality. The study therefore, concludes that Glycine max and Sesamum indicum could alter reproductive hormoness in male Wistar rat offspring.

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Effects Of Glycine Max And Sesamum Indicum On Reproductive Parameters In Male Wistar Rat Offsprings

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